What is SpaceOAR?
SpaceOAR® hydrogel is an option for men who undergo radiation treatment for prostate cancer. It acts as a spacer providing space between the rectum and the prostate, making it much less likely that the rectum is exposed to radiation. It is injected into place prior to the start of radiation treatment. Patients may be awake or asleep under general anesthesia for the procedure. SpaceOAR® hydrogel is not painful, remains stable during radiation therapy and then is gradually absorbed by the body after radiation therapy has been completed.
Why Should I Have SpaceOAR Hydrogel?
The goal of radiation therapy is to maximize radiation to the prostate and to avoid radiating surrounding normal tissue. The prostate and rectum are very close and are only naturally separated by a small space. Due to this closeness, prostate radiation therapy can accidentally cause damage to the rectum. SpaceOAR hydrogel is a gel-like material that temporarily moves the rectal wall away from the prostate during radiotherapy. By separating the prostate from the rectum, SpaceOAR hydrogel reduces radiation dose delivered to the rectum and may eliminate or reduce damage to the rectum. It may also allow your doctor to enhance radiation treatment to your prostate to better target the cancer or to reduce the total number of treatment sessions
SpaceOAR is intended to temporarily position the anterior rectal wall away from the prostate during radiotherapy for prostate cancer and in creating this space it is the intent of SpaceOAR hydrogel to reduce the radiation dose delivered to the anterior rectum. The SpaceOAR hydrogel is composed of biodegradable material and maintains space for the entire course of prostate radiotherapy treatment. It is completely absorbed by the patient’s body over time.
Clinical data comparing patients with and without SpaceOAR hydrogel demonstrated the benefits of SpaceOAR hydrogel to include reduction of rectal toxicity resulting in improved bowel function, improvements in urinary function, and a higher likelihood to maintain sexual function.
Potential complications associated with SpaceOAR hydrogel include but are not limited to pain associated with SpaceOAR hydrogel injection; pain or discomfort associated with SpaceOAR hydrogel, needle penetration of the bladder, prostate, rectal wall, rectum, or urethra; injection of SpaceOAR hydrogel into the bladder, prostate, rectal wall, rectum, or urethra; local inflammatory reactions; infection; injection of air, fluid or SpaceOAR hydrogel intravascularly; urinary retention; rectal mucosal damage, ulcers, necrosis; bleeding; constipation; and rectal urgency.